Periodic fasting starves cisplatin‐resistant cancers to death
نویسندگان
چکیده
منابع مشابه
Ceramide starves cells to death by downregulating nutrient transporter proteins.
Ceramide induces cell death in response to many stimuli. Its mechanism of action, however, is not completely understood. Ceramide induces autophagy in mammalian cells maintained in rich media and nutrient permease downregulation in yeast. These observations suggested to us that ceramide might kill mammalian cells by limiting cellular access to extracellular nutrients. Consistent with this propo...
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Introduction: In many cultures fasting is recommended as a way to protect and promote health. However, there are few studies on the effects of fasting on organ function and resistance to toxic agents such as drugs. This study was conducted to investigate the effect of short-term periodic fasting on the acetaminophen hepatotoxic effects in mice. Methods: In this...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2018
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.201899815